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Showing posts from May, 2025

The Link Between Cancer Stem Cells and Immunotherapy Resistance

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  Despite significant breakthroughs in immunotherapy , many cancer patients experience resistance , either initially (primary resistance) or after an initial response (acquired resistance). A growing body of research points to a major culprit behind this resistance: Cancer Stem Cells (CSCs) . Understanding the connection between cancer stem cells and immunotherapy resistance could unlock new strategies for overcoming treatment failure and achieving lasting remission in cancer patients. What Are Cancer Stem Cells? Cancer Stem Cells (CSCs) are a subpopulation of cancer cells that possess characteristics similar to normal stem cells. These include: Self-renewal Differentiation Tumor initiation Unlike the bulk of tumor cells, CSCs are often dormant or slow-dividing , making them more resistant to chemotherapy, radiation , and, as recent studies suggest, immunotherapy . How Do Cancer Stem Cells Resist Immunotherapy? Immunotherapy, including checkpoint inhibitors,...

Ovarian Cancer: What Every Woman Needs to Know

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  Ovarian Cancer: What Every Woman Needs to Know Ovarian cancer is often referred to as the “silent killer” because its symptoms are subtle and often go unnoticed until the disease has progressed. It is the fifth leading cause of cancer-related deaths among women, and it’s vital that women understand the risks, symptoms, and the importance of early detection. Whether you're looking to educate yourself, a loved one, or raise awareness, this blog provides essential insights every woman should know. What Is Ovarian Cancer? Ovarian cancer begins in the ovaries—female reproductive glands that produce eggs, estrogen, and progesterone. Most ovarian cancers are either epithelial tumors (starting in the surface cells of the ovary) or germ cell tumors (starting in the cells that produce eggs). Key Statistics: About 1 in 78 women will develop ovarian cancer in her lifetime. It most commonly affects women over 50, but it can occur at any age. When detected early, the ...

The Role of Immunotherapy in Advanced Liver Cancer

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  The Role of Immunotherapy in Advanced Liver Cancer 11th International Cancer, Oncology and Therapy Conference | September 02-04, 2025 | Dubai, UAE & Online https://cancer.utilitarianconferences.com Introduction Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the most challenging malignancies worldwide due to its asymptomatic nature in early stages, limited treatment options, and poor prognosis in advanced stages. While traditional treatments such as surgery, chemotherapy, and targeted therapies have provided limited success in advanced cases, immunotherapy has emerged as a beacon of hope for transforming the treatment landscape. As we prepare for the 11th International Cancer, Oncology and Therapy Conference (11CANCERUCG2025) , held from September 02–04, 2025 in Dubai, UAE , leading researchers, oncologists, and healthcare professionals will gather to explore cutting-edge developments in cancer care — with a major focus on revolutionizing ...

Types of Radiotherapy: Which One Is Right for You?

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  Radiotherapy, also known as radiation therapy, is one of the most widely used and effective treatments in the fight against cancer. It uses high doses of radiation to destroy or damage cancer cells by disrupting their ability to grow and divide. Depending on the type, location, and stage of cancer, as well as individual patient needs, different forms of radiotherapy may be recommended. Understanding the different types of radiotherapy can help patients and caregivers make informed decisions about treatment options—and feel more confident throughout the care journey. In light of growing global interest in personalized cancer therapies, the 11th International Cancer, Oncology and Therapy Conference , taking place from September 02–04, 2025 in Dubai, UAE , will bring together experts and students to discuss innovations in radiotherapy and other critical areas of oncology. Major Types of Radiotherapy        1. External Beam Radiation Therap...

Beyond DNA: The Role of Epigenetics in Cancer Development and Treatment

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  For decades, scientists believed that the key to understanding cancer lay solely within the genetic code—mutations in DNA that drive uncontrolled cell growth. While genetics remains a foundational pillar of cancer biology, a new dimension of discovery has emerged: epigenetics . Epigenetics refers to heritable changes in gene expression that occur without altering the underlying DNA sequence . These modifications act like switches and dimmers, turning genes on or off or adjusting their intensity. In the context of cancer, these switches can become faulty, leading to the silencing of tumor suppressor genes or the activation of oncogenes, even when the DNA sequence itself remains unmutated. What Is Epigenetics? To grasp epigenetics, think of DNA as the script of a play. While the script (genetic code) remains the same, the performance can vary drastically depending on how it’s directed and acted out. Epigenetic mechanisms—such as DNA methylation , histone modification , and no...